JWH is an analgetic. It is a member of the indole category. JWH-018 can act as a cannabinoid agonist towards the CB1 and CB2 sensory receptors. It has been found to produce effects similar to that of THC with a longer continuance of action.

The abbreviation J.W.H. stands for John W. Huffman who is considered the inventor of JWH-018. It is a chemical first synthesized in 1995 in a university lab in the United States. JW Huffman earned his BS from Northwestern University and his AM and PhD from Harvard. He began his academic career at Georgia Institute of Technology (1957-60) and joined Clemson as assistant professor in 1960. He was an NSF Predoctoral Fellow at Harvard and received an NIH Career Development Award (1965-70). He was a visiting professor at Colorado State University (1982). The principal emphasis in Dr. Huffman’s research group is on the synthesis of analogues and metabolites of delta-9-tetrahydrocannabinol THC), the principal active component of marijuana. JW Huffman has published dozen of articles about cannabinoids.

Although toxicity reports are not completed by an independant research lab, scientist state they are inclined to believe that it is not toxic.
Further information about JWH-018 toxicity reports can be found on JWH-018 toxicity